Other services

IVT Yield Improvement Screening Service

Optimize in vitro transcription (IVT) reactions to maximize mRNA synthesis yield. Based on condition screening combining multiple parameters such as enzymes, buffers, reaction temperature, and time, we propose the optimal reaction composition.

dsRNA Reduction (IVT Process)

Effectively remove and reduce double-stranded RNA (dsRNA), a byproduct of IVT reactions, to enhance the purity and safety of mRNA products. We also detect and quantify dsRNA, supporting a smooth transition from pilot production to GMP manufacturing.

Yield

dsRNA

Quality Testing Services (GMP Compliant)

We offer contract testing services for various tests required for pharmaceutical quality, such as mRNA structure verification and impurity analysis. Utilizing our domestic GMP-compliant facilities, we have established a rapid and flexible testing system.

Circular RNA Prototyping

We offer prototyping of circular RNA, which has high intracellular stability and is expected to express proteins for long periods of time. We provide a consistent process from design to purification.

Design and Prototyping of Special RNA (Consultation Required)

We flexibly handle the design and prototyping of special RNA molecules, such as modified bases, short-chain and long-chain structures, and complex secondary structures. Based on prior consultation, we propose the optimal synthesis protocol according to your specifications.

Ribosome measurement

We offer quantitative measurement of intracellular ribosome levels, which is essential for evaluating mRNA translation efficiency. We provide comprehensive support from experimental design to measurement.

Establishment and transfer of various analytical technologies

We provide one-stop support from the establishment of various analytical technologies to technology transfer. We also offer protocol optimization, in-house implementation, and staff training support.