@charset "utf-8";
/* head,text */


.h_style01{
	font-size:32px;
	font-weight:bold;
	color:#333;
	text-align:center;
	margin-bottom:40px;
}
.h_style01 span{
	padding:30px 30px 20px;
	display:inline-block;
	border-top:#E60012 solid 4px;
}
.h_style01 sub{
	display:block;
	font-size:18px;
	color:#E50012;
	font-weight: normal;
	font-family:'Century';
}
.h_style02{
	text-align:center;
	font-size:24px;
	font-weight:bold;
	color:#1F1F1F;
	margin-bottom:25px;
}
.h_style02.large{
	font-size:32px;
}
.h_style03{
	display:block;
	font-size:28px;
	font-weight:bold;
	text-align:center;
	color:#E50012;
	margin-bottom:60px;
}
.h_style03 sub{
	display:block;
	font-size:19px;
	color:#1F1F1F;
	margin-top:10px;
}
.h_style04{
	font-size:20px;
	font-weight:bold;
	color:#1F1F1F;
	padding:5px 20px;
	border-left:#1F1F1F solid 4px;
	margin-bottom:20px;
}
.h_style05{
	font-size:18px;
	font-weight:bold;
	margin-bottom:10px;
}
p.text,
.texts > p{
	font-size:1rem;
	line-height:1.875;
	text-align:left;
}
.f_small{
	font-size:0.875rem;
}
.mb1em{
	margin-bottom:1.875em;
}
.mb2em{
	margin-bottom: 3.75em;
}

.limit_lh p{
	display: -webkit-box;
    overflow: hidden;
    -webkit-line-clamp: 1;
    -webkit-box-orient: vertical;
}

@media screen and (max-width: 768px) {
	p.text,
	.texts > p{
		font-size:1rem;
	}
}

/* Link */

.text_link a,
a.text_link{
	text-decoration:underline;
	transition: color 0.4s;
	text-decoration-thickness:1px;
}
.text_link a:hover,
a.text_link:hover{
	text-decoration:none;
	color:inherit;
}
.block_link a,
a.block_link{
	display:block;
	transition: background 0.4s, color 0.4s, border 0.4s;
}
.block_link a img{
	transition: opacity 0.4s;
}
.block_link a:hover,
a.block_link:hover{
	text-decoration:none;
}
.block_link a:hover img,
a:hover img.opacity{
	opacity: 0.7;
	text-decoration:none;
}
.common_btn{
	text-align:center;
	margin:2em auto 3em;
}
.common_btn a{
	position: relative;
	z-index: 10;
	display: flex;
	align-items: center;
	justify-content: left;
	max-width: 140px;
	color: #0064ba;
	width: 100%;
	margin-left: auto;
	margin-right: 0;
	min-height: 40px;
	padding: 10px 30px 10px 0px;
	text-decoration: none;
	transition: background 0.3s;
	overflow: hidden;
}
.common_btn a::after{
	position: absolute;
	content: "→";
	width: auto;
	height: 18px;
	background-size: cover;
	top: 0;
	bottom: 0;
	left: auto;
	right: 1px;
	margin: auto;
	transition: right 0.3s;
}
.common_btn a::before {
	position: absolute;
	z-index: 10;
	display: inline-block;
	content: "";
	width: 100%;
	height: 1px;
	background: #0064ba;
	bottom: 0px;
	left: 0px;
	transform: scale(1, 1);
	transform-origin: left center;
	transition: transform 0.4s ease 0s;
}
@media (any-hover: hover) {
	.common_btn a:hover:after{
		right: 5px;
	}
}
.common_btn2{
	text-align:center;
}
.common_btn2.btn_cdmo{
	--btn_color: #556fb5;
}
.common_btn2.btn_ips{
	--btn_color: #489191;
}
.common_btn2 a{
	display: inline-flex;
	max-width: 330px;
	width: 100%;
	justify-content: center;
	align-items: center;
	text-decoration: none !important;
	border: solid 1px #ffffff;
	border-radius: 0;
	color: #ffffff;
	background: var(--btn_color);
	font-size: min(1.2rem , 1.35vw);
	word-break: auto-phrase;
	font-weight: 500;
	padding: 0.5em 2em 0.5em 2em;
	min-height: 76px;
	position: relative;
	z-index: 0;
	text-decoration: none;
	margin: 1em 0;
	transition: background .4s, color .4s, transform .4s;
}
.common_btn2 a::after{
	position: absolute;
	content: "→";
	font-size: 1.125rem;
	display: block;
	color: #fff;
	width: 1em;
	height: 10px;
	position: absolute;
	z-index: 10;
	margin: auto;
	line-height: 1;
	transform: translateY(-5px);
	transition: color .4s;
	inset: 0 1em 0 auto;
}
@media (any-hover: hover) {
	.common_btn2 a:hover{
		color: var(--btn_color);
		background: #fff;
	}
	.common_btn2 a:hover:after{
		color: var(--btn_color);
	}
}
@media screen and (max-width:767px) {
	.common_btn{
		margin:1em auto 1em;
	}
	.common_btn a{
		max-width: 160px;
		padding: 0.5em 2em;
		margin: auto;
	}
	.common_btn a span{
		padding-right: 0;
	}
	.common_btn2 a{
		font-size: 1em;
		padding: 0.5em 2em 0.5em 2em;
		min-height: 60px;
		margin: 0;
	}
}
a.arrow_link,
.arrow_link a{
	position: relative;
	padding-left:14px;
}
a.arrow_link:before,
.arrow_link a:before{
    content: "";
    position: absolute;
    left: -1px;
    margin-top:-3px;
    top: 50%;
    width: 6px;
    height: 6px;
    border-top: 2px solid #666;
    border-right: 2px solid #666;
    -webkit-transform: rotate(45deg);
    transform: rotate(45deg);
}

.ico_blank{position:relative;padding-right: 20px;}
.ico_blank:before, .ico_blank:after{
	content: "";
	width: 11px;
	height: 11px;
	display: inline-block;
	position: absolute;
	border: 1px solid #333;
	background:#fff;
	right: 0;
	top: 2px;
	z-index:10;
}
.ico_blank:after{
	right: 3px;
	top: 5px;
	z-index:9;
}
img.icon{
	vertical-align:middle;
	margin-right:5px;
}
/* image */
.scale_m { 
	max-width:100%;
	width:auto;
	height:auto;
}
.scale_all{	
	width:100%;
	height:auto;
}
.img_fit{
	position:relative;
	width:100%;
	padding-bottom:63%;
	display:flex;
	align-items:center;
	justify-content:center;
	overflow:hidden;
}
.img_fit img{
	position:absolute;
	top:0;
	left:0;
	bottom:0;
	right:0;
	margin:auto;
	max-width:100%;
	max-height:100%;
	transition:transform .4s;
	display:block;
}
a.img_fit:hover img,
a:hover .img_fit img{
	transform:scale(1.05);
}
@media screen and (max-width: 768px) {
	.scale {
		width:100%;
		height:auto;
	}
}

/* table,list */

.table_style {
	border:#ddd solid 1px;
	border-bottom:none
}
.table_style dl{
	position:relative;
	border-bottom:#ddd solid 1px;
	width:100%;
}
.table_style dt{
	position:absolute;
	top:0;
	left:0;
	background:#EEEEEE;
	width:250px;
	padding:16px 20px;
	box-sizing:border-box;
}
.table_style dd{
	padding:16px 20px;
	padding-left:270px;
	box-sizing:border-box;
}
.list_style ul li{
	margin-left:1em;
	margin-bottom:5px;
	text-indent: -1em;
}
.list_style ul li:before{
	content:"\30FB";
	margin-right:5px;
	color:#005BAC;
	font-weight:bold;
	
}
.list_style ul li.inlist ul{
	margin-top:5px;
}
.list_style ul li.inlist li{
	margin-left:3em;
	padding-left:0;
	text-indent:-3em;
}
.ol_style ol li{
	margin-left:-1em;
	padding-left:1em;
	margin-bottom:5px;
	text-indent: -1em;
	list-style-position:inside;
}

.dl_style dl{
	margin:0;
	padding:15px;
	background:#f6f6f6;
}
.dl_style dl dt{
	font-weight:bold;
	margin-bottom:10px;
	padding-bottom:10px;
	border-bottom: dotted 1px #999;
}
.table_wrap {
	margin:40px 0;
}
.table_wrap.overs {
	padding-bottom:10px;
	overflow-x:auto;
	overflow-y:hidden;
}
.table_wrap table{
	width:100%;
	box-sizing:border-box;
	font-size:16px;
}
.table_wrap table th,
.table_wrap table td{
	box-sizing:border-box;
	padding:20px;
	border:solid 1px #ddd;
}


.table_wrap::-webkit-scrollbar {
	height: 15px;
}

.table_wrap::-webkit-scrollbar-track {
	border-radius: 10px;
	background: #c1c1c1;
}

.table_wrap::-webkit-scrollbar-thumb {
	border-radius: 10px;
	background: #666;
}
@media only screen and (max-width: 768px) {
	.table_style dl,
	.table_style dt,
	.table_style dd{
		display:block;
	}
	.table_style dt{
		border-bottom:#ddd solid 1px;
		width:100%;
		padding:10px;
		position:static;
		top:auto;
		left:auto;
	}
	.table_style dd{
		padding:15px 10px;
	}
	.dl_style dl{
		font-size:14px;
		margin:0;
	}
	.table_wrap{
		overflow-x:auto;
	}
	.table_wrap table{
		font-size:12px;
	}
	.table_wrap table th,
	.table_wrap table td{
		padding:10px;
	}
}
.topics_list li{
	border-bottom:#DDDDDD solid 1px;
	margin: 0;
}
.topics_list li a,
.topics_list li > div{
	display:flex;
	flex-wrap:wrap;
	align-items: flex-start;
	padding: 2em 0.2em;
	gap: 1em 2%;
	text-decoration: none !important;
}
.topics_list time,
.topics_list p{ 
	display:inline-block;
}
.topics_list time{
	font-size: 0.875rem;
	color: #0064ba;
	width: 17%;
	min-width: 9em;
}
.topics_list .cat{
	font-size: 0.85rem;
	font-weight: 500;
	display: inline-block;
}
.topics_list .cat_box{
	display: flex;
	gap: 0.5em 1em;
	flex-wrap: wrap;
	width: 77%;
}

.topics_list .cat em{
	font-size: 0.75rem;
	margin-left: 0.75em;
	padding: 0.1em 1em;
	border: 1px solid;
}
.topics_list .cat.cat_ev-cdmo em,
.topics_list .cat.cat_news-cdmo em{
	color: #556fb5;
}
.topics_list .cat.cat_ev-ips em,
.topics_list .cat.cat_news-ips em{
	color: #489191;
}

.topics_list .article_text{
	width: 100%;
	font-size: 1.125rem;
	display: -webkit-box;
    -webkit-box-orient: vertical;
    -webkit-line-clamp: 3;
    overflow: hidden;
}
@media (any-hover: hover){
	.topics_list li a:hover{
		background: #f8f8fa;
	}
}
@media screen and (max-width:767px) {
	.topics_list time{
		width: 100%;
	}
	.topics_list li a{
		padding: 1em 0.2em;
	}
	.topics_list .cat_box{
		width: 100%;
	}
}
/*  パンくずリスト  */
#pan {
	padding-top: 30px;
	padding-bottom: 60px;
	font-size: 0.875rem;
}
#pan ol {
	padding: 0;
	margin: 0;
	font-size: 0.75rem;
	display: flex;
	align-items: center;
	overflow-y: hidden;
	overflow-x: auto;
}
#pan li,
#pan li * {
	display: inline-block;
	vertical-align: middle;
}
#pan li * {
	display: inline;
	vertical-align: middle;
}
#pan li {
	margin: 0 0.5em 0 0;
	white-space: nowrap;
}
#pan li a {
	text-decoration: underline;
	color: #004ea2;
}
#pan li a:hover {
	text-decoration: none;
}
#pan li:before {
	content: "\003E";
	display: inline-block;
	margin-right: 0.5em;
	vertical-align: middle;
}
#pan li:first-child:before {
	content: "";
	display: none;
	margin-right: 0;
}
@media only screen and (max-width: 767px) {
	#pan {
		padding: 0;
		margin: 15px;
		overflow: hidden;
		position: relative;
		z-index: 2;
		white-space: nowrap;
	}
	#pan:after,
	#pan li:last-child:after {
		content: "";
		display: block;
		position: absolute;
		top: 0;
		bottom: 0;
		right: 0;
		width: 10px;
		z-index: 1;
		background: rgb(0, 0, 0);
		background: linear-gradient(-90deg, rgba(0, 0, 0, 0.2) 0%, rgba(0, 0, 0, 0) 50%);
	}
	#pan a {
		text-decoration: underline;
	}
	#pan ul {
		padding: 0;
		margin: 0;
		overflow-x: scroll;
		overflow-y: hidden;
	}
	#pan ol {
		position: relative;
		z-index: 4;
	}
	#pan li a {
		text-decoration: underline;
	}
	#pan li:last-child {
		position: relative;
		padding-right: 10px;
		margin-right: 0;
		flex-grow: 1;
	}
	#pan li:last-child:after {
		top: -1em;
		bottom: -1em;
		background: rgb(255, 255, 255);
		background: linear-gradient(90deg, rgba(255, 255, 255, 0) 0%, rgba(255, 255, 255, 1) 50%);
	}
	#pan li:before {
		transform: translateY(4px);
	}
}
/*  ページャー  */
.pager_style{
	text-align:center;
	padding:30px 0 0 0;
}
.pager_style li{
	width:40px;
	border:1px solid #BBBBBB;
	background:#fff;
	display:inline-block;
	margin:0 0 10px 0;
}
.pager_style li:hover{
	background:#024384;
}
.pager_style li.on{
	background:#024384;
}
.pager_style li a{
	font-size:16px;
	text-decoration:none;
	display:block;
	padding:8px 0;
}
.pager_style li.on a{
	color:#fff;
}
.pager_style li a:hover{
	color:#fff;
}
.pager_style li.prev{
	margin:0 10px 0 0;
}
.pager_style li.next{
	margin:0 0 0 10px;
}
@media screen and (max-width: 768px) {
	.pager_style li{
		width: 30px;
	}
	.pager_style li a{
		font-size:12px;
		padding:6px 0;
	}
	.pager_style li.prev,
	.pager_style li.next{
		margin:0;
	}
}

.pc_center { }
.pc_right { }
.sp_center { }
.sp_right { }


@media screen and (min-width:769px) {
	.pc_center { text-align:center !important;}
	.sp_center { text-align:left;}
	.pc_right { text-align:right !important;}
	.mb50_h{ margin-bottom:50px !important;}
	.mb60_h{ margin-bottom:60px !important;}
	.mb80_h{ margin-bottom:80px !important;}
}
@media screen and (max-width:767px) {
	.pc_center,
	.pc_righ { text-align:left;}
	.sp_center { text-align:center !important;}
	.sp_right { text-align:right !important;}
	.mb50_h{ margin-bottom:25px !important;}
	.mb60_h{ margin-bottom:30px !important;}
	.mb80_h{ margin-bottom:40px !important;}
}

.modal-content { 
	width: 80%;
	max-width: 1240px;
	margin: 0px;
	padding: 10px 20px;
	background: none;
	position: fixed;
	display: none;
	z-index:1020;
}
#modal-overlay { 
	z-index: 1000;
	display: none;
	position: fixed;
	top: 0px;
	left: 0px;
	width: 100%;
	height: 120%;
	background-color: rgba(0, 0, 0, 0.66);

}
.modal_tit { 
	position: fixed;
	top: 0px;
	left: 0px;
	right: 0px;
	margin: auto;
	max-width: 250px;
	text-align: center;
	line-height: normal;
	font-size: 20px;
	z-index: 1025;
	overflow: hidden;
	padding: 0px 30px;color:#fff;
}
.modal_tit span {
	display: block;
	position: relative;
	padding: 10px 0px;
	background: rgb(0, 0, 0);
	z-index: 2;
	border-bottom: 1px solid rgb(255, 255, 255);
}
.modal-content .close_btn {
	position: absolute;
	top: -10%;
	right: 0px;
	color: rgb(255, 255, 255);
	font-size: 40px;
	line-height: 1;
	display: block;
	cursor: pointer;
}

@media screen and (max-width: 768px) {
	modal-content { width: 100%;
	padding: 15px;
	box-sizing: border-box;
}
}
/*  タブ切替  */
.tab_change>input[type="radio"] {
	position: absolute;
	z-index: -100;
	width: 0;
	top: 0;
	left: 0;
}
.tab_change>input[type="radio"]~.tab_views .tab_content {
	position: relative;
	z-index: -10;
	max-height: 0;
	overflow: hidden;
	opacity: 0;
	transition: opacity .4s;
}
.tab_change>input[id$="01"]:checked~.tab_views *[class$="01"],
.tab_change>input[id$="02"]:checked~.tab_views *[class$="02"],
.tab_change>input[id$="03"]:checked~.tab_views *[class$="03"],
.tab_change>input[id$="04"]:checked~.tab_views *[class$="04"],
.tab_change>input[id$="05"]:checked~.tab_views *[class$="05"]{
	z-index: 10;
	max-height: 100%;
	overflow: visible;
	opacity: 1;
}
.tab_list {
	display: flex;
	justify-content: space-between;
	flex-direction: column;
	align-items: stretch;
	width: 100%;
	padding: 0;
	margin-bottom: 2em;
	width: 27%;
}
.tab_list li {
	flex: 1;
	margin: 0;
}
.tab_list li label{
	position: relative;
	display: flex;
	justify-content: space-between;
	align-items: center;
	padding: 1em;
	z-index: 100;
	font-size: 1rem;
	font-weight: 600;
	text-align: left;
	border-bottom: 1px solid #d7d7d7;
	min-width: 297px;
}
.tab_list li label span{
	min-width: 6em;
}
.tab_list li label em{
	border: 1px solid;
	padding: 0.25em 1em;
	min-width: 10.5em;
	text-align: center;
	font-size: 0.9em;
}
.tab_list li label[for="tab_01"]{
	border-top: 1px solid #d7d7d7;
}
.tab_list li label[for="tab_02"],
.tab_list li label[for="tab_04"]{
	border: none;
	padding-bottom: 0.5em;
}
.tab_list li label[for="tab_02"] em,
.tab_list li label[for="tab_04"] em{
	color: #489191;
}
.tab_list li label[for="tab_03"],
.tab_list li label[for="tab_05"]{
	padding-top: 0.5em;
	justify-content: flex-end;
}
.tab_list li label[for="tab_03"] span,
.tab_list li label[for="tab_05"] span{
	display: none;
}
.tab_list li label[for="tab_03"] em,
.tab_list li label[for="tab_05"] em{
	color: #556fb5;

}
.tab_change>input[id$="01"]:checked~.tab_controller *[for$="01"],
.tab_change>input[id$="02"]:checked~.tab_controller *[for$="02"],
.tab_change>input[id$="03"]:checked~.tab_controller *[for$="03"],
.tab_change>input[id$="04"]:checked~.tab_controller *[for$="04"], 
.tab_change>input[id$="05"]:checked~.tab_controller *[for$="05"]{
	color: #0063b9;
	background: #f8f8fa;
}
.tab_change>input[id$="03"]:checked~.tab_controller *[for$="02"],
.tab_change>input[id$="05"]:checked~.tab_controller *[for$="04"]{
	color: #0063b9;
}
.tab_change>input[id$="02"]:checked~.tab_controller *[for$="02"] em,
.tab_change>input[id$="04"]:checked~.tab_controller *[for$="04"] em{
	color: #FFF;
	background: #489191;
}
.tab_change>input[id$="03"]:checked~.tab_controller *[for$="03"] em, 
.tab_change>input[id$="05"]:checked~.tab_controller *[for$="05"] em{
	color: #FFF;
	background: #556fb5;
}
@media (any-hover: hover) {
	.tab_list li label:hover{
		background: #f8f8fa;
	}
}
@media screen and (max-width: 767px) {
	.tab_list {
		margin-bottom: 1em;
	}
	.tab_list li label {
		font-size: 1rem;
		padding: 0.75em 0.25em;
	}
	.tab_change .tab_controller label:before {
		border-width: 10px 4px 0 4px;
		inset: auto 0 -10px;
	}
}
